Bruker has announced numerous new product introductions for research, industrial and applied markets, designed to deliver more confident analyses with increased sensitivity, specificity and productivity, as well as novel scientific capabilities which expand the boundaries of molecular and materials research.
Magnetic Resonance Spectroscopy and Preclinical Imaging:
Assure – Aloe vera: This new module expands the capabilities of Bruker’s Assure – RMS (Raw Material Screening) NMR solutions. Fully automated, quantitative and qualitative NMR (Nuclear Magnetic Resonance) analysis enables Aloe vera screening in the cosmetics, natural products and pharmaceutical industries. Given the high demand for this versatile plant, the material identity, quality and quantity of key components, in both raw extract and finished products, need to be analyzed. Identity can be determined via the presence of key metabolites, and freshness is assessed from degradation products.
Assure Chemometrics Module: The Assure-RMS chemometrics module delivers increased confidence in product conformity and materials classification in the polymer, pharmaceutical and dietary supplement industries, and in metabolomics studies. Together with the identification and quantification of key components, it provides in-depth details of materials composition and rapidly detects non-conforming material. Due to the high reproducibility of NMR, it enables the transfer of chemometric models to other laboratories without having to recollect data.
CryoProbe Prodigy TCI: The expanded CryoProbe Prodigy TCI probe range, now available from 500 to 700 MHz, is bringing its major boost in sensitivity at an affordable price to even more NMR users. The triple-resonance Prodigy TCI uses nitrogen-cooled RF coils and preamplifiers to deliver proton sensitivity enhancements of a factor of 2.5x, and carbon sensitivity enhancements of 2x over room temperature probes, thus offering a ‘300 MHz-equivalent’ sensitivity boost for 500, 600 and 700 MHz NMRs at relatively low cost.
Complete Molecular Confidence (CMC) 2.0: This key update significantly enhances the original software for improved in-line, integrated routine workflows for interactive quantitation, as well as structure verification and structure elucidation. Chemists will benefit from CMC 2.0’s improved integration of automated acquisition, processing and reporting, together with faster algorithm performance for step-by-step interactive workflow assistance. CMC 2.0 includes various modules which automatically assign NMR signals to structural characteristics, conduct structural consistency assessments, deliver spectral analysis and enable easy structure elucidation, culminating in compact reports for easy transfer to publications, journals or patent applications.
First 527 GHz Solid State DNP-NMR System: After its successful installation at the University of Utrecht, Netherlands, the world’s highest field Dynamic Nuclear Polarization (DNP) – NMR system is now driving new research applications in biomolecular and material science. DNP significantly enhances the sensitivity of solid-state NMR by 1-2 orders of magnitude by transferring polarization from the electron spins to the nuclear spins. DNP-NMR enables completely new scientific methods on new categories of samples, with the potential to deliver ever more detailed insights into interactions at the molecular level.
Frank H. Laukien, Ph.D., Bruker’s President and CEO, commented, “Bruker continues to set the pace in our industry for world-class Innovation with Integrity for our global customer base. With compact, easy-to-use, affordable, yet high performance products we gain access to broader markets and expand our presence in quality control, applied and industrial markets, while maintaining our excellent reputation in the scientific research community.”