Bangs Laboratories has launched Streptavidin Magnefy superparamagnetic microspheres, adding a new product line to its portfolio of magnetic particles for life science separations. The new beads bring another option for immobilizing biotinylated antibodies or other proteins, capturing biotinylated PCR products or binding biotinylated ssDNA or dsDNA for downstream applications.
The ~1µm high-performance beads superparamagnetic microspheres have a rapid separation profile, offering a performance-driven solid phase for magnetic particle-based applications including SPRI-based total DNA isolation, also molecular and immunoassays. SPRI (Solid Phase Reversible Immobilization) bead technology uses paramagnetic beads to selectively bind nucleic acids by type and size, and is employed for high-performance isolation, purification and cleanup protocols in biotech laboratories.
The new particle can serve as an OEM magnetic SPRI bead. Many types of magnetic particles are used as the solid phase in bioassays and separations, the company notes. While their superparamagnetic properties may be similarly amenable to automation and high-throughput workflows, their specific physical and optical characteristics permit the development of highly tailored reagents for specific assay systems, formats, and platforms.
“In the case of our new magnetic microparticle, Magnefy, we endeavored to manufacture a product with both broad application to assay development, and for focused use in nucleic acid isolation,” explain Bangs Labs scientists. The microspheres are comprised of a proprietary polymer core with an iron oxide layer and carboxylated polymer encapsulation. For more info, see www.bangslabs.com.