At the Experimental Nuclear Magnetic Resonance Conference, held in April at Asilomar, California, Bruker unveiled several new nuclear magnetic resonance products and workflow solutions designed to expand performance, sensitivity, and automation across research and applied NMR. The introductions span console electronics, quantitative chemistry, benchtop FT-NMR, solid-state and dissolution Dynamic Nuclear Polarization (DNP), and digital workflows that support reproducible, unattended and data-driven automation.
Featuring a cryogen-free permanent magnet, the Fourier 80 Duo establishes 80 MHz as an affordable standard for labs transitioning from 60 MHz instruments. With advanced gradient capabilities, solvent suppression and inverse spectroscopy capabilities, the benchtop Fourier 80 Duo delivers high-quality 1D/2D FT-NMR spectra for chemistry. No liquid nitrogen or helium is needed due to the magnet design.
Bruker is expanding its dynamic nuclear polarization (DNP) portfolio with new standard‑bore DNP probes for solid‑state NMR that enable ultra‑high sensitivity on 600 and 800 MHz standard‑bore magnets, as well as on 1.0 and 1.2 GHz systems. These technologically very demanding SB-DNP probes support biosolids applications with HCN designs and extend high-field solid-state DNP for materials applications through fixed-channel configurations. DNP technology combines NMR with microwave irradiation to dramatically boost signal sensitivity.
Complementing these solid‑state DNP capabilities, the Dynamis dissolution DNP system enables liquids applications, which were impractical with conventional sensitivity limits. With up to 30,000x ¹³C signal enhancement and 5x–10x faster polarization, the Dynamis supports reproducible, higher‑throughput solution‑state NMR and metabolic MRI studies in catalysis or chemical kinetics.
Bruker also introduced enhanced NMR solutions for structural biology, laboratory automation, and data-driven research and analytical workflows. NMRtist provides AI‑assisted protein NMR data analysis from multidimensional peak picking through resonance assignment and structure calculation also for non-NMR-experts. The new RNA drug discovery by NMR toolkit offers access to optimized experiments, guided workflows, and resources for RNA structure, dynamics, binding studies, and RNA modification analysis, where NMR is the gold standard for solving RNA structures. In solid-state NMR, 160 kHz magic‑angle‑spinning (MAS) solutions enable high-resolution HCN studies of membrane proteins, protein aggregates, and complex biological assemblies.
“Our ENC 2026 introductions reflect our focus on innovation with impact through NMR technologies and workflows designed to improve productivity, performance and ease-of-use in order to deliver reproducible research and applied results,” said Frank Laukien, CEO. “These advances further increase the impact of labs generating unique, high-value NMR insights to work efficiently, automate complex tasks, and complement other methods in structural biology, molecular dynamics, bio-condensates, disordered proteins, membrane proteins and aggregates, as well as in chemistry and small molecule applied, pharma and industrial applications.” For more info, see www.bruker.com.
